Cheap Otay Mesa, CA motels and hotels

Discount hotels, motel reservations in Otay Mesa, California.

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Holiday Inn Express San Diego - Otay Mesa
2296 Niels Bohr Court
Otay Mesa, CA 92154

Rates from

$85

*

Quality Suites San Diego Otay Mesa
2351 Otay Center Drive
Otay Mesa, CA 92154

Rates from

$76

*

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* Please perform a hotel availability search for actual rates at the time of your stay. Prices listed above are average/estimated rates and may be different based on your check-in date, hotel occupancy, season, etc...